Concomitant use of dihydrocodeine and sedative medicines for example benzodiazepines or similar drugs may well end in sedation, respiratory depression, coma and Demise. As a result of these risks, concomitant prescribing with these sedative medicines must be reserved for patients for whom alternative treatment alternatives are impossible. If a decision is made to prescribe dihydrocodeine concomitantly with sedative medicines, the bottom successful dose ought to be utilized, plus the length of treatment ought to be as quick as you possibly can (see also common dose suggestion in section 4.
Naloxone really should not be administered from the absence of clinically significant respiratory or circulatory depression secondary to dihydrocodeine overdosage.
I preserve staying questioned about strong analgesics in breastfeeding. Tons of people feel unaware that codeine and dihydrocodeine audio identical but don't have a similar threat in breastfeeding.
Naloxone really should be administered cautiously to individuals that are known, or suspected, to generally be physically dependent on dihydrocodeine. In these situations, an abrupt or entire reversal of opioid effects may precipitate pain and an acute withdrawal syndrome.
Drug Interactions Whilst specific medicines shouldn't be employed alongside one another whatsoever, in other cases two different medicines could possibly be applied alongside one another whether or not an interaction could possibly manifest. In these situations, your health care provider should want to change the dose, or other safeguards might be essential.
Belching clumsiness low human body temperature sleepiness weak or feeble pulse weight obtain Other side effects not listed might also take place in some patients. For those who recognize any other effects, Examine with your healthcare Qualified.
Central Nervous Technique The principal actions of therapeutic worth of dihydrocodeine are analgesia and an antitussive result (depression on the cough reflex by immediate impact on the cough centre within the medulla). Antitussive effects might come about with doses reduced than those ordinarily needed for analgesia.
Employing this medicine if you are Expecting, Specifically during the later on A part of pregnancy may lead to critical undesirable effects, like neonatal withdrawal syndrome in the new child little one. Tell your medical doctor immediately if you believe you are pregnant or if you propose to become pregnant even though using this medicine. Contact your medical doctor instantly should you have worsening of pain, enhanced sensitivity to pain, or new pain following having this medicine. These might be symptoms of opioid-induced hyperalgesia and allodynia. Look at with your physician right away in case you or your child have stress, restlessness, a quick heartbeat, fever, sweating, muscle mass spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that aren't there. These might be symptoms of a significant condition called serotonin syndrome. Your hazard could possibly be higher for those who also take sure other medicines that affect serotonin degrees in your body. Applying far too much of the medicine might cause decreased infertility (struggling to have little ones) or may well cause a delay in ovulation for Women of all ages and will affect their capability to have small children. Chat with your medical professional before utilizing this medicine if you plan to have small children. Never take other medicines click here Except if they have been reviewed with your health care provider. This consists of prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin dietary supplements. Side Effects
Do not retain out-of-date or unwelcome medicines. Take them to your local pharmacy which will get rid of them for yourself.
Dihydrocodeine để cai nghiện và điều trị duy trì ở những người bị rối loạn sử dụng thuốc phiện
Dihydrocodeine is improved right into a strong opioid drug (dihydromorphine) in Your entire body. In some people, this change occurs quicker and more wholly than regular, which enhances the danger of incredibly severe side effects.
Get medical help straight away in the event you have any really significant side effects, which includes: fainting, seizure.
There is a threat of building serotonin syndrome with concomitant utilization of opioids and serotonergic medicine(s). The danger may differ according to the medicine combination.
Aspirin can be a nonsteroidal anti-inflammatory drug (NSAID) that's applied To ease pain and lower fever in patients. Caffeine is often a CNS stimulant that is definitely employed together with pain relievers to extend their impact. It's also been used for migraine headaches. Dihydrocodeine belongs for the group of medicines called narcotic analgesics (pain medicines). It acts to the central anxious system (CNS) To alleviate pain. When dihydrocodeine is employed for a long time or in significant doses, it may well become habit-forming, causing psychological or Actual physical dependence. Even so, folks who have continuing pain mustn't Allow the dread of dependence hold them from employing narcotics To ease their pain.